The Heat Inactivation of Vaccinia Virus

Inactivation of vaccinia virus by gamma radiation.

1,1mg I plus 0,42 mg DL-Phenylalanin-(l-14C) wur­ den in 15 cm3 Wasser gelöst. 1.22 mg II wurden in 15 cm3 Wasser mit 0,5 cm3 7i/lOO-NaOH in das wasser­ lösliche Mono-Natriumsalz überführt und 0,42 mg d l Phenylalanin-(l-14C) zugefügt. Versuchsdauer 48 Stun­ den. Die Isolierung und Reinigung der Isoflavone er­ folgte wie im vorigen Versuch. Ausbeuten: Versuch 1. 4,8 mg Biochanin-A und 1,88 mg F...

Protection of vaccinia from heat inactivation by nucleotide triphosphates.

The presence of adenosine triphosphate, guanosine triphosphate, cytosine triphosphate, or uridine triphosphate reduced the rate of inactivation of vaccinia when heated at 50 C. The virus-associated nucleoside triphosphate phosphohydrolases (adenosine triphosphatase, guanosine triphosphatase, cytosine triphosphatase, and uridine triphosphatase) and ribonucleic acid polymerase were also protected...

Enzymic inactivation of vaccinia virus with a bacterial protease.

pepsin (Dawson and McFarlane, 1948 ; Peter and Stoeckenius, 1954). For the purpose of finding out any enzyme to affect the surface structure of vaccinia virus under less radical conditions than with pepsin (pH 3.0), attempts were made to test various enzymes for the effect on the infectivity of the virus. Virus suspension was prepared from the homogenate of infected chorioallantoic membranes (C...

The Inactivation of the Virus of Infectious Myxomatosis by Heat.

Culture on the Chick Chorio-allantois as a Test of Inactivation of Vaccinia Virus.

There is considerable evidence of an empirical nature to indicate that the habitual use as a gargle and mouth wash, of an antiseptic solution so mild that it may be tolerated in contact with the mucous membrane, affords some degree of protection against upper respiratory infections. Thomson and Thomson (1932) writing in regard to prevention of colds have said "Probably one of the most important...